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1

Development of a Fast Screening Method for Selecting Excipients in Formulations using MD simulations, NMR and MicroScale Thermophoresis

Indrakumar, Sowmya, Zalar, Matja, Tschammer, Nuska, Pohl, Christin, NÃ¸rgaard, Allan, Streicher, Werner, Harris, Pernille, Golovanov, Alexander P., H. J. Peters, GÃ¼nther

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2020

File:

PDF, 2.05 MB

2020

2

Discovery of Highly Potent and Neurotensin Receptor 2 Selective Neurotensin Mimetics

Einsiedel, Jürgen, Held, Cornelia, Hervet, Maud, Plomer, Manuel, Tschammer, Nuska, Hübner, Harald, Gmeiner, Peter

Journal:

Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 1.00 MB

english, 2011

3

Visualization and ligand-induced modulation of dopamine receptor dimerization at the single molecule level

Tabor, Alina, Weisenburger, Siegfried, Banerjee, Ashutosh, Purkayastha, Nirupam, Kaindl, Jonas M., Hübner, Harald, Wei, Luxi, Grömer, Teja W., Kornhuber, Johannes, Tschammer, Nuska, Birdsall, Nigel J.

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 2.08 MB

english, 2016

4

Identification of novel allosteric modulators for the G-protein coupled US28 receptor of human cytomegalovirus

Ana Kralj, Alexander Wetzel, Shohreh Mahmoudian, Thomas Stamminger, Nuska Tschammer, Markus R. Heinrich

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 402 KB

english, 2011

5

Fast and Efficient 18 F-Labeling by [ 18 F]Fluorophenylazocarboxylic Esters

Fehler, Stefanie K., Maschauer, Simone, Höfling, Sarah B., Bartuschat, Amelie L., Tschammer, Nuska, Hübner, Harald, Gmeiner, Peter, Prante, Olaf, Heinrich, Markus R.

Journal:

Chemistry - A European Journal

Year:

2014

Language:

english

File:

PDF, 1.21 MB

english, 2014

6

The Azulene Framework as a Novel Arene Bioisostere: Design of Potent Dopamine D4 Receptor Ligands Inducing Penile Erection

Stefan Löber, Nuska Tschammer, Harald Hübner, Maria Rosaria Melis, Antonio Argiolas, Peter Gmeiner

Journal:

Year:

2009

Language:

english

File:

PDF, 341 KB

english, 2009

7

Recent advances in the search for D3- and D4-selective drugs: probes, models and candidates

Stefan Löber, Harald Hübner, Nuska Tschammer, Peter Gmeiner

Journal:

Trends in Pharmacological Sciences

Year:

2011

Language:

english

File:

PDF, 627 KB

english, 2011

8

[Topics in Medicinal Chemistry] Chemokines Volume 14 ||

Tschammer, Nuska

Year:

2015

Language:

english

File:

PDF, 23.07 MB

english, 2015

9

[Topics in Medicinal Chemistry] Chemokines Volume 14 || Chemokine Receptors in Allergy, Inflammation, and Infectious Disease

Tschammer, Nuska

Year:

2015

Language:

english

File:

PDF, 641 KB

english, 2015

10

Cross-Receptor Interactions between Dopamine D 2L and Neurotensin NTS 1 Receptors Modulate Binding Affinities of Dopaminergics

Koschatzky, Susanne, Tschammer, Nuska, Gmeiner, Peter

Journal:

ACS Chemical Neuroscience

Year:

2011

Language:

english

File:

PDF, 1.41 MB

english, 2011

11

Dopamine D 2 , D 3 , and D 4 Selective Phenylpiperazines as Molecular Probes To Explore the Origins of Subtype Specific Receptor Binding

Ehrlich, Katharina, Götz, Angela, Bollinger, Stefan, Tschammer, Nuska, Bettinetti, Laura, Härterich, Steffen, Hübner, Harald, Lanig, Harald, Gmeiner, Peter

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 3.72 MB

english, 2009

12

Identifying Modulators of CXC Receptors 3 and 4 with Tailored Selectivity Using Multi-Target Docking

Schmidt, Denis, Bernat, Viachaslau, Brox, Regine, Tschammer, Nuska, Kolb, Peter

Journal:

ACS Chemical Biology

Year:

2015

Language:

english

File:

PDF, 1.24 MB

english, 2015

13

The interaction of LCK and the CD4 co-receptor alters the dose response of T-cells to interleukin-7

Christina Kittipatarin, Nuska Tschammer, Annette R. Khaled

Journal:

Immunology Letters

Year:

2010

Language:

english

File:

PDF, 1.67 MB

english, 2010

14

Identification of Two Distinct Sites for Antagonist and Biased Agonist Binding to the Human Chemokine Receptor CXCR3

Milanos, Lampros, Saleh, Noureldin, Kling, Ralf C., Kaindl, Jonas, Tschammer, Nuska, Clark, Timothy

Journal:

Angewandte Chemie International Edition

Year:

2016

Language:

english

File:

PDF, 1.94 MB

english, 2016

15

Identification of Two Distinct Sites for Antagonist and Biased Agonist Binding to the Human Chemokine Receptor CXCR3

Milanos, Lampros, Saleh, Noureldin, Kling, Ralf C., Kaindl, Jonas, Tschammer, Nuska, Clark, Timothy

Journal:

Angewandte Chemie

Year:

2016

Language:

english

File:

PDF, 2.79 MB

english, 2016

16

SS2-6 The interaction of LCK and the CD4 co-receptor alters the dose response of T-cells to Interleukin-7

Christina Kittipatarin, Nuska Tschammer, Annette R. Khaled

Journal:

Year:

2010

Language:

english

File:

PDF, 40 KB

english, 2010

17

Synthesis and Biological Evaluation of Biphenyl Amides That Modulate the US28 Receptor

Kralj, Ana, Kurt, Elif, Tschammer, Nuska, Heinrich, Markus R.

Journal:

Year:

2014

Language:

english

File:

PDF, 743 KB

english, 2014

18

Radiosynthesis and validation of 18F-FP-CMT, a phenyltropane with superior properties for imaging the dopamine transporter in living brain

Cumming, Paul, Maschauer, Simone, Riss, Patrick J, Tschammer, Nuska, Fehler, Stefanie K, Heinrich, Markus R, Kuwert, Torsten, Prante, Olaf

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2014

Language:

english

File:

PDF, 560 KB

english, 2014

19

Novel D3 Selective Dopaminergics Incorporating Enyne Units as Nonaromatic Catechol Bioisosteres: Synthesis, Bioactivity, and Mutagenesis Studies

Dörfler, Miriam, Tschammer, Nuska, Hamperl, Katharina, Hübner, Harald, Gmeiner, Peter

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 341 KB

english, 2008

20

Molecular mechanisms of biased and probe-dependent signaling at CXCR3 induced by negative allosteric modulators

Brox, Regine, Milanos, Lampros, Saleh, Noureldin, Baumeister, Paul, Buschauer, Armin, Hofmann, Dagmar, Heinrich, Markus R, Clark, Timothy, Tschammer, Nuska

Journal:

Molecular Pharmacology

Year:

2018

Language:

english

File:

PDF, 2.06 MB

english, 2018

21

Specific Delivery of Therapeutic RNAs to Cancer Cells via the Dimerization Mechanism of phi29 Motor pRNA

Guo, Songchuan, Tschammer, Nuska, Mohammed, Sulma, Guo, Peixuan

Journal:

Human Gene Therapy

Year:

2005

Language:

english

File:

PDF, 19.63 MB

english, 2005

22

Active-State Model of a Dopamine D2 Receptor - Gαi Complex Stabilized by Aripiprazole-Type Partial Agonists

Kling, Ralf C., Tschammer, Nuska, Lanig, Harald, Clark, Timothy, Gmeiner, Peter, Seifert, Roland

Journal:

Year:

2014

Language:

english

File:

PDF, 1.32 MB

english, 2014

23

Development of Flavonoid-Based Inverse Agonists of the Key Signaling Receptor US28 of Human Cytomegalovirus

Kralj, Ana, Nguyen, Mai-Thao, Tschammer, Nuska, Ocampo, Nicolette, Gesiotto, Quinto, Heinrich, Markus R., Phanstiel, Otto

Journal:

Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 1.04 MB

english, 2013

24

[Topics in Medicinal Chemistry] Chemokines Volume 14 || Allosteric Modulation of Chemokine Receptors

Tschammer, Nuska

Year:

2015

Language:

english

File:

PDF, 792 KB

english, 2015

25

Ligand selectivity of a synthetic CXCR4 mimetic peptide

Groß, Andrea, Brox, Regine, Damm, Dominik, Tschammer, Nuška, Schmidt, Barbara, Eichler, Jutta

Journal:

Bioorganic & Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 1017 KB

english, 2015

26

154 The Membrane-binding Activity of the Apoptotic Protein, BAX, is Regulated Through Novel Intermolecular Interactions

Nuska Tschammer, Thomas L. Selby, Annette R. Khaled

Journal:

Year:

2007

Language:

english

File:

PDF, 69 KB

english, 2007

27

Discovery of dopamine D4 receptor antagonists with planar chirality

Sanna, Fabrizio, Ortner, Birgit, Hübner, Harald, Löber, Stefan, Tschammer, Nuska, Gmeiner, Peter

Journal:

Bioorganic & Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 473 KB

english, 2013

28

Highly Potent 5-Aminotetrahydropyrazolopyridines: Enantioselective Dopamine D3 Receptor Binding, Functional Selectivity, and Analysis of Receptor−Ligand Interactions

Tschammer, Nuska, Elsner, Jan, Goetz, Angela, Ehrlich, Katharina, Schuster, Stefan, Ruberg, Miriam, Kühhorn, Julia, Thompson, Dawn, Whistler, Jennifer, Hübner, Harald

Journal:

Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 1.14 MB

english, 2011

29

Allosteric modulation of the G protein-coupled US28 receptor of human cytomegalovirus: Are the small-weight inverse agonist of US28 ‘camouflaged’ agonists?

Tschammer, Nuska

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2014

Language:

english

File:

PDF, 907 KB

english, 2014

30

[Topics in Medicinal Chemistry] Chemokines Volume 14 || Exploring the CXCR3 Chemokine Receptor with Small-Molecule Antagonists and Agonists

Tschammer, Nuska

Year:

2015

Language:

english

File:

PDF, 12.25 MB

english, 2015

31

[Topics in Medicinal Chemistry] Chemokines Volume 14 || Role of 3D Structures in Understanding, Predicting, and Designing Molecular Interactions in the Chemokine Receptor Family

Tschammer, Nuska

Year:

2015

Language:

english

File:

PDF, 1.05 MB

english, 2015

32

Synthesis and biological evaluation of chemokine receptor ligands with 2-benzazepine scaffold

Thum, Simone, Kokornaczyk, Artur, Seki, Tomoaki, De Maria, Monica, Ortiz Zacarias, Natalia V., de Vries, Henk, Weiss, Christina, Koch, Michael, Schepmann, Dirk, Kitamura, Masato, Tschammer, Nuska, Hei

Journal:

European Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 769 KB

english, 2017

33

[Topics in Medicinal Chemistry] Chemokines Volume 14 || Selective and Dual Targeting of CCR2 and CCR5 Receptors: A Current Overview

Tschammer, Nuska

Year:

2015

Language:

english

File:

PDF, 7.89 MB

english, 2015

34

Synthesis and Application of the First Radioligand Targeting the Allosteric Binding Pocket of Chemokine Receptor CXCR3

Viachaslau Bernat, Prof. Dr. Markus R. Heinrich, Paul Baumeister, Prof. Dr. Armin Buschauer, Dr. Nuska Tschammer

Journal:

Year:

2012

Language:

english

File:

PDF, 600 KB

english, 2012

35

Interleukins in Cancer Biology: Their Heterogeneous Role. By Arseniy E. Yuzhalin, Anton G. Kutikhin

Tschammer, Nuska

Journal:

Year:

2015

Language:

english

File:

PDF, 175 KB

english, 2015

36

Insight into structural requirements for selective and/or dual CXCR3 and CXCR4 allosteric modulators

Kolarič, Anja, Švajger, Urban, Tomašič, Tihomir, Brox, Regine, Frank, Theresa, Minovski, Nikola, Tschammer, Nuska, Anderluh, Marko

Journal:

European Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 2.24 MB

english, 2018

37

Development of Photoactivatable Allosteric Modulators for the Chemokine Receptor CXCR3

Admas, Tizita Haimanot, Bernat, Viachaslau, Heinrich, Markus R., Tschammer, Nuska

Journal:

Year:

2016

Language:

english

File:

PDF, 633 KB

english, 2016

38

The Chemokine Receptor CXCR3 Isoform B Drives Breast Cancer Stem Cells

Kundu, Namita, Ma, Xinrong, Brox, Regine, Fan, Xiaoxuan, Kochel, Tyler, Reader, Jocelyn, Tschammer, Nuska, Fulton, Amy

Journal:

Breast Cancer Basic and Clinical Research

Year:

2019

File:

PDF, 2.06 MB

2019

39

A Comparison of Chloroambucil- and Xylene-Containing Polyamines Leads to Improved Ligands for Accessing the Polyamine Transport System

Kaur, Navneet, Delcros, Jean-Guy, Imran, Jon, Khaled, Annette, Chehtane, Mounir, Tschammer, Nuska, Martin, Bénédicte, Phanstiel, Otto

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 160 KB

english, 2008

40

Ligand-Biased and Probe-Dependent Modulation of Chemokine Receptor CXCR3 Signaling by Negative Allosteric Modulators

Bernat, Viachaslau, Brox, Regine, Heinrich, Markus R., Auberson, Yves P., Tschammer, Nuska

Journal:

Year:

2015

Language:

english

File:

PDF, 770 KB

english, 2015

41

Boronic Acids as Probes for Investigation of Allosteric Modulation of the Chemokine Receptor CXCR3

Bernat, Viachaslau, Admas, Tizita Haimanot, Brox, Regine, Heinemann, Frank W., Tschammer, Nuska

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 1.75 MB

english, 2014

42

Engineering a GPCR−Ligand Pair That Simulates the Activation of D 2L by Dopamine

Tschammer, Nuska, Dörfler, Miriam, Hübner, Harald, Gmeiner, Peter

Journal:

ACS Chemical Neuroscience

Year:

2010

Language:

english

File:

PDF, 1.68 MB

english, 2010

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